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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 1
2004 3
2005 2
2006 2
2007 1
2008 1
2009 1
2010 1
2011 4
2012 2
2013 3
2014 3
2015 9
2016 7
2017 11
2018 14
2019 17
2020 12
2021 23
2022 10
2023 11
2024 0

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124 results

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Page 1
Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in AD and Rosacea.
Zhang H, Zhang Y, Li Y, Wang Y, Yan S, Xu S, Deng Z, Yang X, Xie H, Li J. Zhang H, et al. Front Immunol. 2021 Nov 23;12:756550. doi: 10.3389/fimmu.2021.756550. eCollection 2021. Front Immunol. 2021. PMID: 34899707 Free PMC article.
There were 747 overlapped DEGs (ol-DEGs) that were detected in AD and rosacea, enriched in inflammation-, metabolism-, and apoptosis-related pathways. Using the TF regulatory network analysis, 37 common TFs and target genes were identified as hub genes. ...In conclusion, t …
There were 747 overlapped DEGs (ol-DEGs) that were detected in AD and rosacea, enriched in inflammation-, metabolism-, and apoptosis- …
Mapping Rora expression in resting and activated CD4+ T cells.
Haim-Vilmovsky L, Henriksson J, Walker JA, Miao Z, Natan E, Kar G, Clare S, Barlow JL, Charidemou E, Mamanova L, Chen X, Proserpio V, Pramanik J, Woodhouse S, Protasio AV, Efremova M, Griffin JL, Berriman M, Dougan G, Fisher J, Marioni JC, McKenzie ANJ, Teichmann SA. Haim-Vilmovsky L, et al. PLoS One. 2021 May 18;16(5):e0251233. doi: 10.1371/journal.pone.0251233. eCollection 2021. PLoS One. 2021. PMID: 34003838 Free PMC article.
We dissect the function of Rora using overexpression and a CD4-conditional Rora-knockout mouse, as well as a RORA-reporter mouse. We establish the importance of Rora in CD4+ T cells for controlling lung inflammation induced by Nippostrongylus br …
We dissect the function of Rora using overexpression and a CD4-conditional Rora-knockout mouse, as well as a RORA-repor …
Rora Regulates Neutrophil Migration and Activation in Zebrafish.
Hsu AY, Wang T, Syahirah R, Liu S, Li K, Zhang W, Wang J, Cao Z, Tian S, Matosevic S, Staiger CJ, Wan J, Deng Q. Hsu AY, et al. Front Immunol. 2022 Mar 4;13:756034. doi: 10.3389/fimmu.2022.756034. eCollection 2022. Front Immunol. 2022. PMID: 35309302 Free PMC article.
RORalpha overexpression reduced interleukin-33 expression and prevented mast cell degranulation and inflammation by inducing autophagy in allergic rhinitis.
Yu W, Du J, Peng L, Zhang T. Yu W, et al. Immun Inflamm Dis. 2023 Oct;11(10):e1017. doi: 10.1002/iid3.1017. Immun Inflamm Dis. 2023. PMID: 37904695 Free PMC article.
Moreover, RORalpha in AR HNEpC cells could prevent mast cell (MC) degranulation and inflammation by accelerating autophagy, RORalpha overexpression inhibited MC degranulation and NLRP3-induced inflammation in the AR model mice. RORalpha overexpression reduced IL-33 …
Moreover, RORalpha in AR HNEpC cells could prevent mast cell (MC) degranulation and inflammation by accelerating autophagy, RORalpha …
The suppressive functions of Rora in B lineage cell proliferation and BCR/ABL1-induced B-ALL pathogenesis.
Li N, Wang N, He W, Feng Y, Qiu Q, Qiu H, Zheng L, Yin Y, Wang B, Sun Y, Pan C, Sample KM, Huang J, Su Z, Li Z, Zhang H, Hu Y. Li N, et al. Int J Biol Sci. 2022 Mar 6;18(6):2277-2291. doi: 10.7150/ijbs.68939. eCollection 2022. Int J Biol Sci. 2022. PMID: 35414788 Free PMC article.
RORA plays an important role in regulating circadian rhythms, inflammation, metabolism and cellular development. ...By using Rora(loxp/loxp) Mx-1-Cre mice, Rora was deleted in hematopoietic cells post Pipc induction. ...
RORA plays an important role in regulating circadian rhythms, inflammation, metabolism and cellular development. ...By using …
Genetic variants in RORA are associated with asthma and allergy markers in an admixed population.
Lima LC, Queiroz GA, Costa RDS, Alcantara-Neves NM, Marques CR, Costa GNO, Barreto ML, Figueiredo CAV, Carneiro VL. Lima LC, et al. Cytokine. 2019 Jan;113:177-184. doi: 10.1016/j.cyto.2018.07.004. Epub 2018 Jul 7. Cytokine. 2019. PMID: 30539779
An efficient memory Th2 cell response is dependent on IL-13 produced by ILC2s, causing allergic lung inflammation and elevated serum levels of immunoglobulin E. ILC2 cells are derived from common lymphoid progenitors and their growing depends on the transcription factor …
An efficient memory Th2 cell response is dependent on IL-13 produced by ILC2s, causing allergic lung inflammation and elevated serum …
Acute and Repeated Ozone Exposures Differentially Affect Circadian Clock Gene Expression in Mice.
Sundar IK, Duraisamy SK, Choudhary I, Saini Y, Silveyra P. Sundar IK, et al. Adv Biol (Weinh). 2023 Nov;7(11):e2300045. doi: 10.1002/adbi.202300045. Epub 2023 May 19. Adv Biol (Weinh). 2023. PMID: 37204107
Circadian rhythms have an established role in regulating physiological processes, such as inflammation, immunity, and metabolism. Ozone, a common environmental pollutant with strong oxidative potential, is implicated in lung inflammation/injury in asthmatics. ...The …
Circadian rhythms have an established role in regulating physiological processes, such as inflammation, immunity, and metabolism. Ozo …
Identification of Immuno-Inflammation-Related Biomarkers for Acute Myocardial Infarction Based on Bioinformatics.
You H, Dong M. You H, et al. J Inflamm Res. 2023 Aug 7;16:3283-3302. doi: 10.2147/JIR.S421196. eCollection 2023. J Inflamm Res. 2023. PMID: 37576155 Free PMC article.
PURPOSE: Previous studies have confirmed that inflammation and immunity are involved in the pathogenesis of acute myocardial infarction (AMI). ...CONCLUSION: In conclusion, eight key immuno-inflammation-related genes, namely, SH2D1B, ADM, PI3, MMP9, NRG1, CBLB, R …
PURPOSE: Previous studies have confirmed that inflammation and immunity are involved in the pathogenesis of acute myocardial infarcti …
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Zhang Y, Liu T, Deng Z, Fang W, Zhang X, Zhang S, Wang M, Luo S, Meng Z, Liu J, Sukhova GK, Li D, McKenzie ANJ, Libby P, Shi GP, Guo J. Zhang Y, et al. Adv Sci (Weinh). 2023 Mar;10(7):e2206958. doi: 10.1002/advs.202206958. Epub 2023 Jan 2. Adv Sci (Weinh). 2023. PMID: 36592421 Free PMC article.
Development of abdominal aortic aneurysms (AAA) enhances lesion group-2 innate lymphoid cell (ILC2) accumulation and blood IL5. ILC2 deficiency in Rora(fl/fl) Il7r(Cre/+) mice or induced ILC2 depletion in Icos(fl-DTR-fl/+) Cd4(Cre/+) mice expedites AAA growth, increases le …
Development of abdominal aortic aneurysms (AAA) enhances lesion group-2 innate lymphoid cell (ILC2) accumulation and blood IL5. ILC2 deficie …
Maternal diabetes-mediated RORA suppression contributes to gastrointestinal symptoms in autism-like mouse offspring.
Xiao L, Wang M, Zhang W, Song Y, Zeng J, Li H, Yu H, Li L, Gao P, Yao P. Xiao L, et al. BMC Neurosci. 2022 Feb 14;23(1):8. doi: 10.1186/s12868-022-00693-0. BMC Neurosci. 2022. PMID: 35164690 Free PMC article.
RESULTS: Male offspring of diabetic dams were treated with either superoxide dismutase (SOD) mimetic MnTBAP or RORA agonist SR1078, or were crossbred with intestine epithelial cells (IEC)-specific RORA knockout (RORA(-/-)) mouse. ...IEC-specific RORA d …
RESULTS: Male offspring of diabetic dams were treated with either superoxide dismutase (SOD) mimetic MnTBAP or RORA agonist SR1078, o …
124 results